5-氨基-1-叔-丁基-3-(1’-萘基甲基)-4-氰基吡唑合成路线 （共 4 条）
反应条件
1: NaH / tetrahydrofuran / 0.5 h / Ambient temperature 2: aq. NaHCO3 / dioxane / 1 h / 80 °C 3: Et3N / ethanol / 1 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 4 p. 627 - 631
反应条件
1: (COCl)2, DMF / diethyl ether 2: NaH / tetrahydrofuran / 0.5 h / Ambient temperature 3: aq. NaHCO3 / dioxane / 1 h / 80 °C 4: Et3N / ethanol / 1 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 4 p. 627 - 631
反应条件
triethylamine in ethanol 1 h; Heating;
参考文献
Journal of the American Chemical Society, , vol. 121, # 4 p. 627 - 631
反应条件
in ethanol 1 h; Reflux;
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 7 p. 3068 - 3077
