ammonia; 4,5-bis(dicyclohexylphosphinomethyl)acridine in tetrahydrofuran T=140°C; P=26402.6 Torr; 21 h; AutoclaveInert atmosphere; Product distribution / selectivity;

ammonia; 4,5-bis(dicyclohexylphosphinomethyl)acridine in 1,1-dimethylpropan-1-ol T=150°C; P=28427.8 Torr; 18 h; AutoclaveInert atmosphere; Product distribution / selectivity;

hydrogen; nickel in methanol 20 h;

1: 65 percent / NH2OH*HCl, NaOAc / ethanol / 4 h / 50 °C 2: 51 percent / H2, Raney Ni / methanol / 20 h View Scheme

1: 93 percent / BaMnO4 / 1,2-dichloro-ethane / 4.5 h / 113 °C 2: 65 percent / NH2OH*HCl, NaOAc / ethanol / 4 h / 50 °C 3: 51 percent / H2, Raney Ni / methanol / 20 h View Scheme

1: Duolite C 204 F ionexchange resin (H form) / H2O; various solvent(s) / 16 h / Heating; a.) reflux, 16 h; 2.) r.t., 2 h 2: 93 percent / BaMnO4 / 1,2-dichloro-ethane / 4.5 h / 113 °C 3: 65 percent / NH2OH*HCl, NaOAc / ethanol / 4 h / 50 °C 4: 51 percent / H2, Raney Ni / methanol / 20 h View Scheme