(S)-(-)-1-苯基-1-丁醇合成路线 （共 63 条）
反应条件
EL-03 lipase T=30°C; 101 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 23, # 8 p. 583 - 586
反应条件
1: H2 / Pd-Pb-CaCO3 2: PCC 3: 1.) MCPBA, 2.) p-TSA*pyridine, MeOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 104, # 25 p. 7371 - 7372
反应条件
hydrogen; palladium on activated charcoal Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 104, # 26 p. 7667 - 7669
反应条件
dilithium salt of (2S,5S)-2, 5-diisopropylpiperazine 1) toluene, hexane, RT, 30 min, 2) RT, 20h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2717 - 2720
反应条件
Toyonite-200M-supported Burkholderia cepacia lipase I287F/I290A mutant in di-isopropyl ether T=30°C; 50 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Ema, Tadashi; Nakano, Yasuko; Yoshida, Daiki; Kamata, Shusuke; Sakai, Takashi
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 31 p. 6299 - 6308
反应条件
Rhizopus nigricans (sterile potato dextrose medium) in tetrahydrofuran 16 h; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ziffer, Herman; Kawai, Ken-ichi; Kasai, Masaji; Imuta, Mitsuru; Froussios, Cleanthis
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 3017 - 3021
反应条件
1: 1.) PdCl2((R)-N,N-dimethyl-1-<(S)-2-(diphenylphosphino)ferrocenyl>ethylamine) / 1.) RT, 1 h, 2.) RT, 22 h 2: H2 / 5percent Pd-C / ethanol / 760 Torr 3: KF, m-CPBA / dimethylformamide / 18 h / Ambient temperature View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 499, # 1.2 p. 167 - 172
反应条件
1: H2 / 5percent Pd-C / ethanol / 760 Torr 2: KF, m-CPBA / dimethylformamide / 18 h / Ambient temperature View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 499, # 1.2 p. 167 - 172
反应条件
dihydrogen peroxide 5 h; chloroperoxidase from Caldaromyces fumago, citrate buffer pH=5.0; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 117, # 42 p. 10419 - 10424
反应条件
hydrogen; platinum on activated charcoal in methanol Ambient temperature;
参考文献
Chemische Berichte, , vol. 114, # 1 p. 375 - 383
