(R)-(+)-1-苯基-1-丁醇合成路线 （共 41 条）
反应条件
hydrogen; palladium on activated charcoal Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 104, # 26 p. 7667 - 7669
反应条件
dilithium salt of (2S,5S)-2, 5-diisopropylpiperazine 1) toluene, hexane, RT, 30 min, 2) RT, 20h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2717 - 2720
反应条件
Toyonite-200M-supported Burkholderia cepacia lipase I287F/I290A mutant in di-isopropyl ether T=30°C; 50 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Ema, Tadashi; Nakano, Yasuko; Yoshida, Daiki; Kamata, Shusuke; Sakai, Takashi
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 31 p. 6299 - 6308
反应条件
Rhizopus nigricans (sterile potato dextrose medium) in tetrahydrofuran 16 h; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ziffer, Herman; Kawai, Ken-ichi; Kasai, Masaji; Imuta, Mitsuru; Froussios, Cleanthis
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 3017 - 3021
反应条件
dihydrogen peroxide 5 h; chloroperoxidase from Caldaromyces fumago, citrate buffer pH=5.0; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 117, # 42 p. 10419 - 10424
反应条件
n-butyllithium; (2S,2'S)-2-hydroxymethyl-1-lt;(1-methylpyrrolidine-2-yl)methylgt;pyrrolidine in toluene T=-110°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 37, # 23 p. 4111 - 4119
反应条件
1,) chiral catalyst 2.) diethyl ether, -120 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 103, # 15 p. 4585 - 4586
参考文献
Journal of the Chemical Society, Chemical Communications, , # 6 p. 405 - 406
反应条件
tetra-n-butylammonium tetrafluoroborate; (1R,2S)-(-)-N,N-dimethylephedrinium tetrafluoroborate in water; N,N-dimethyl-formamide Electrolysis;
参考文献
Yadav, Ashok K.; Singh, Arpita
Bulletin of the Chemical Society of Japan, 2002 , vol. 75, # 3 p. 587 - 588
反应条件
1: triphenyl boroxine With diethylzinc in hexane T=60°C; 10 h; Sealed vesselInert atmosphere; 2: With diethylzinc; (Ra)-N-[(1S,2R)-1,2-diphenyl-2-hydroxyethyl]-3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]-azepine in hexane; toluene T=20°C; 0.5 h; Inert atmosphere; 3: butyraldehyde optical yield given as percent eeenantioselective reactionFurther stages;
参考文献
Chirality, , vol. 22, # 1 p. 159 - 164
