(R)-(+)-1-苯基-1-丁醇合成路线 （共 41 条）
反应条件
lithium aluminium tetrahydride in diethyl ether 6 h; Heating;
参考文献
Tetrahedron Asymmetry, , vol. 7, # 11 p. 3285 - 3294
反应条件
1: Et3N 2: H2, quinoline / Pd/BaSO4 4: H2 / Pd/C 5: 1.) BF3*2AcOH, 2.) MCPBA, Et3N View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 18 p. 1456 - 1457
反应条件
1: 56 percent / alumina / 24 h / Heating 2: 89 percent / imidazole / dimethylformamide / 3 h / 20 °C 3: 86 percent / LiAlH4 / diethyl ether / 1 h / 20 °C 4: 52 percent / pyridine; DMAP / 2 h / 20 °C 5: 92 percent / LiAlH4 / diethyl ether / 1 h / 20 °C 6: AcOH; H2O / tetrahydrofuran / 24 h / 40 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 12 p. 1685 - 1694
反应条件
1: 89 percent / imidazole / dimethylformamide / 3 h / 20 °C 2: 86 percent / LiAlH4 / diethyl ether / 1 h / 20 °C 3: 52 percent / pyridine; DMAP / 2 h / 20 °C 4: 92 percent / LiAlH4 / diethyl ether / 1 h / 20 °C 5: AcOH; H2O / tetrahydrofuran / 24 h / 40 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 12 p. 1685 - 1694
反应条件
1: H2 / Pd/C 2: 1.) BF3*2AcOH, 2.) MCPBA, Et3N View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 18 p. 1456 - 1457
反应条件
1: H2, quinoline / Pd/BaSO4 3: H2 / Pd/C 4: 1.) BF3*2AcOH, 2.) MCPBA, Et3N View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 18 p. 1456 - 1457
反应条件
1: Ph3P 2: H2 / Pd/C 3: 1.) BF3*2AcOH, 2.) MCPBA, Et3N View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 18 p. 1456 - 1457
反应条件
1: H2, quinoline / Pd/BaSO4 2: Ph3P 3: H2 / Pd/C 4: 1.) BF3*2AcOH, 2.) MCPBA, Et3N View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 18 p. 1456 - 1457
反应条件
2: H2 / Pd/C 3: 1.) BF3*2AcOH, 2.) MCPBA, Et3N View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 18 p. 1456 - 1457
反应条件
molecular sieve; lipase B from Candida antarctica in 1,4-dioxane T=30°C; 163 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 21 p. 3047 - 3052
