1: acetic acid 2: aq. HCl / aq. ethanol View Scheme

1.1: thionyl chloride / toluene; dimethylformamide / 25 h / 20 °C 1.2: 89.8 percent / toluene; dimethylformamide / 5 h / 20 °C 2.1: 92.2 percent / Alcalase (R) / toluene; aq. phosphate buffer / 50 h / 35 °C / pH 8.0 3.1: 83.8 percent / 10 percent HCl / H2O / 24 h / Heating View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '19284879', constants.ctx, '0')">polymer incarcerated Pd(PPh₃)4</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '2037554', constants.ctx, '0')">sulfuric acid</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3739113', constants.ctx, '0')">phenylmethyltriethylammonium bromide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102551', constants.ctx, '0')">1,4-dioxane</a> <br />T=120&deg;C;&nbsp;P=45600&nbsp;Torr;&nbsp;15&nbsp;h;&nbsp;<br /> &nbsp;