1-苄基-3-羟基-1H-吲唑合成路线 （共 6 条）
反应条件
sodium hydroxide in water T=35 - 70°C;
参考文献
Sokolenko; Yagupolskii
Chemistry of Heterocyclic Compounds, 2011 , vol. 46, # 11 p. 1335 - 1343
反应条件
sodium hydroxide in dimethyl sulfoxide T=20°C; 24 h;
参考文献
WO2003/76408 A2, ;
Page/Page column 28 ;
反应条件
hydrogenchloride; sodium hydroxide; sodium nitrite 2.) 5 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 24, # 34 p. 3651 - 3652
反应条件
in methanol T=20°C; 6 h; Irradiation;
参考文献
Journal of Pharmaceutical Sciences, , vol. 82, # 4 p. 371 - 372
反应条件
1: 95 percent / pyridine / CH2Cl2 2: 1.) (Me3Sn)2 / 1.) Pd(PPh3)4 / 1.) dioxane, reflux, 2.) dioxane, reflux 3: LiBH4 / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Gordon, David W.
Synlett, 1998 , # 10 p. 1065 - 1066
反应条件
in diethyl ether; dichloromethane
1.5 h; Ambient temperature;
参考文献
Bruneau; Delvare; Edwards; McMillan
Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1028 - 1036
