反应条件
1: 1.)t-BuLi / 1.) cyclohexane/pentane, room temp., 24 h; 2.) ether, -78 deg C, 1 h, room temp., 3 h
2: 100 percent Chromat. / acetyl chloride, pyridine / CH2Cl2 / 12 h
3: 92 percent Chromat. / H2 / Pd/C (5percent) / ethanol / 36 h
4: 92 percent / BBr3 / CH2Cl2; hexane / 1.) -78 deg C, 3 h; 2.) room temp., 20 h
5: 1.) NaH / 1.) DMF, room temp., 30 min; 2.) 1 h
6: 61 percent Chromat. / DDQ / toluene / 4 h / Heating
View Scheme
参考文献
Kirby, Anthony J.; Percy, Jonathan M.
Tetrahedron, 1988 , vol. 44, # 22 p. 6911 - 6920
