反应条件
1: 91.5 percent / N-bromosuccinimide / CCl4 / 4 h / Heating; Irradiation
2: 49 percent / 99percent nitric acid, 96percent sulfuric acid / acetic anhydride / 0.17 h / -30 °C
3: 92 percent / dimethylformamide / 1 h / Ambient temperature
4: 91 percent / triethylamine, H2 / 10percent palladium on carbon / methanol / 1.5 h / 3800 Torr / Ambient temperature
5: 1.) triethylamine; 2.) 5percent HCl / 1.) CH2Cl2, refl., 30 min; 2.) 60 deg C, 3 h
6: 72 percent / pentan-1-ol / 2 h / Heating
View Scheme
参考文献
Toja, Emilio; Francesco, Giuseppe Di; Barone, Domenico; Baldoli, Emiliana; Corsico. Nerina; Tarzia, Giorgio
European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 221 - 228
