1,2,3,4-四氢-1-萘胺合成路线 （共 44 条）
反应条件
Candida antarctica lipase B; hydrogen; nickel in toluene T=70°C; P=75.0075 Torr; 72 h; AutoclaveEnzymatic reaction; optical yield given as percent ee;
参考文献
Parvulescu, Andrei N.; Jacobs, Pierre A.; De Vos, Dirk E.
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 1 p. 113 - 121
反应条件
Candida antarctica lipase B in di-isopropyl ether T=60°C;
参考文献
Skupinska, Krystyna A.; McEachern, Ernest J.; Baird, Ian R.; Skerlj, Renato T.; Bridger, Gary J.
Journal of Organic Chemistry, 2003 , vol. 68, # 9 p. 3546 - 3551
反应条件
Novozym® 435 (lipase B from C. antarctica, recombinant, expressed in Aspergillus niger, adsorbed on acrylic resin) in toluene T=0 - 70°C; Flow reactorEnzymatic reaction; Kinetics; TemperatureReagent/catalyst; stereoselective reaction;
参考文献
Boros, Zoltan; Falus, Peter; Markus, Maria; Weiser, Diana; Olah, Mark; Hornyanszky, Gabor; Nagy, Jozsef; Poppe, Laszlo
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 85-86, p. 119 - 125
反应条件
coated protease in 3-methyl pentan-3-ol T=21°C; 456 h; Resolution of racemateEnzymatic reaction; enantioselective reaction;
参考文献
Queyroy, Severine; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1759 - 1764
反应条件
N,N'-dimethyl-N,N'-propyleneurea T=-20°C; 24 h; Title compound not separated from byproducts;
参考文献
Sabot, Cyrille; Subhash, Pithani V.; Valleix, Alain; Arseniyadis, Stellios; Mioskowski, Charles
Synlett, 2008 , # 2 p. 268 - 272
反应条件
in isopropyl alcohol
参考文献
Pharmacia and Upjohn S.p.A.
Patent: US5965563 A1, 1999 ;
反应条件
sodium hydroxide in dichloromethane
pH=9;
参考文献
Leopoldo, Marcello; Berardi, Francesco; Colabufo, Nicola A.; Contino, Marialessandra; Lacivita, Enza; Niso, Mauro; Perrone, Roberto; Tortorella, Vincenzo
Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6616 - 6624
反应条件
sodium hydroxide in dichloromethane
pH=9;
参考文献
Leopoldo, Marcello; Berardi, Francesco; Colabufo, Nicola A.; Contino, Marialessandra; Lacivita, Enza; Niso, Mauro; Perrone, Roberto; Tortorella, Vincenzo
Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6616 - 6624
参考文献
FACULTES UNIVERSITAIRES NOTRE-DAME DE LA PAIX; MASEREEL, Bernard; FREDERICK, Raphael; SUPURAN, Claudiu, T.
Patent: WO2012/175654 A1, 2012 ;
Location in patent: Page/Page column 36-37 ;
参考文献
American Cyanamid Company
Patent: US4049717 A1, 1977 ;
