6-溴-1,2,3,4-四氢喹啉合成路线 （共 12 条）
反应条件
N-bromosuccinmide in tetrachloromethane T=20°C; 3 h;
参考文献
Marchand, Pascal; Puget, Alain; Le Baut, Guillaume; Emig, Peter; Czech, Michael; Guenther, Eckhard
Tetrahedron, 2005 , vol. 61, # 16 p. 4035 - 4041
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 1 h; Heating / reflux; 2: With sodium hydroxide; water T=20°C;
参考文献
US2004/220206 A1, ;
Page 24; 32 ;
US 20040220206 A1
反应条件
lithium aluminium tetrahydride; aluminium trichloride in tetrahydrofuran T=60°C;
参考文献
Varnes, Jeffrey G.; Wacker, Dean A.; Jacobson, Irina C.; Quan, Mimi L.; Ellis, Christopher D.; Rossi, Karen A.; He, Ming Y.; Luettgen, Joseph M.; Knabb, Robert M.; Bai, Steven; He, Kan; Lam, Patrick Y.S.; Wexler, Ruth R.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 23 p. 6481 - 6488
反应条件
perchloric acid; [{(η5-C5Me5)IrCl}2(μ-Cl)2] in water 17 h; Heating;
参考文献
Tetrahedron Letters, , vol. 45, # 16 p. 3215 - 3217
反应条件
diisobutylaluminium hydride in hexane; dichloromethane T=20°C; 3 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 16, # 17 p. 7956 - 7967
反应条件
bromine in chloroform T=-78°C; 2 h;
参考文献
Tetrahedron, , vol. 64, # 43 p. 10068 - 10074
参考文献
Chemische Berichte, , vol. 16, p. 735
反应条件
1: 60 percent / dimethylformamide / 16 h / Heating 2: 95 percent / hydrogen peroxide; NaOH / H2O / 24 h / Heating View Scheme
参考文献
Marchand, Pascal; Puget, Alain; Le Baut, Guillaume; Emig, Peter; Czech, Michael; Guenther, Eckhard
Tetrahedron, 2005 , vol. 61, # 16 p. 4035 - 4041
参考文献
Kunckell
Berichte der Deutschen Pharmazeutischen Gesellschaft, vol. 20, p. 191
Chem. Zentralbl., 1910 , vol. 81, # II p. 93
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=120°C; 2 h;
参考文献
BIOENERGENIX; MCCALL, John, M.; ROMERO, Donna, L.
Patent: WO2012/94462 A2, 2012 ;
Location in patent: Page/Page column 60-61 ;
WO 2012/094462 A2
