5-(4-甲氧基苯基)-3,4-二氢-2H-吡咯合成路线 (共 10 条)
反应条件
in dichloromethane
T=0°C; 48 h;
参考文献
Sun, Xiaowei; Gao, Chengzhe; Zhang, Fan; Song, Zhuang; Kong, Lingyi; Wen, Xiaoan; Sun, Hongbin
Tetrahedron, 2014 , vol. 70, # 3 p. 643 - 649
反应条件
3,3-dimethylbut-1-ene; RhCl(CO)(PFur3)2; caesium carbonate in 1,4-dioxane
T=120°C; 12 h;
参考文献
Sezen, Bengue; Sames, Dalibor
Journal of the American Chemical Society, 2004 , vol. 126, # 41 p. 13244 - 13246
反应条件
triethyl phosphite in dimethyl sulfoxide
0.166667 h; microwave irradiation;
参考文献
Singh, Pradeep N.D.; Klima, Rodney F.; Muthukrishnan, Sivaramakrishnan; Murthy, Rajesh S.; Sankaranarayanan, Jagadis; Stahlecker, Heidi M.; Patel, Bhavika; Gudmundsdottir, Anna D.
Tetrahedron Letters, 2005 , vol. 46, # 24 p. 4213 - 4217
反应条件
sodium azide; triethyl phosphite in dimethyl sulfoxide
intramolecular aza-Wittig reaction; 0.333333 h; microwave irradiation;
参考文献
Singh, Pradeep N.D.; Klima, Rodney F.; Muthukrishnan, Sivaramakrishnan; Murthy, Rajesh S.; Sankaranarayanan, Jagadis; Stahlecker, Heidi M.; Patel, Bhavika; Gudmundsdottir, Anna D.
Tetrahedron Letters, 2005 , vol. 46, # 24 p. 4213 - 4217
反应条件
zirconium triflate; toluene-4-sulfonamide in 1,2-dichloro-ethane
T=60°C; 48 h;
参考文献
Shi, Min; Yang, Yong-Hua; Xu, Bo
Synlett, 2004 , # 9 p. 1622 - 1624
反应条件
in tetrahydrofuran
3 h; Inert atmosphereReflux;
参考文献
Chang, Mingxin; Li, Wei; Hou, Guohua; Zhang, Xumu
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 18 p. 3121 - 3125
反应条件
1: pyrrolidin-2-one With chloro-trimethyl-silane; triethylamine in diethyl ether
0.5 h; Heating;
2: 4-methoxyphenyl magnesium bromide in diethyl ether
3 h; Heating;
参考文献
Coindet, Cecile; Comel, Alain; Kirsch, Gilbert
Tetrahedron Letters, 2001 , vol. 42, # 35 p. 6101 - 6104
反应条件
1:
2: With hydrogen cation
Further stages.;
参考文献
Nenajdenko; Pronin; Balenkova
Russian Chemical Bulletin, 2007 , vol. 56, # 2 p. 336 - 344
反应条件
ethanol; nickel
Hydrogenation;
参考文献
Burckhalter; Short
Journal of Organic Chemistry, 1958 , vol. 23, p. 1281,1285
反应条件
1.1: isopropylmagnesium chloride / tetrahydrofuran / 1.33 h / -25 °C
1.2: 1.33 h / -75 °C
2.1: dichloromethane / 48 h / 0 °C
View Scheme
参考文献
Sun, Xiaowei; Gao, Chengzhe; Zhang, Fan; Song, Zhuang; Kong, Lingyi; Wen, Xiaoan; Sun, Hongbin
Tetrahedron, 2014 , vol. 70, # 3 p. 643 - 649