1,3,5-三苯甲酰基-D-呋喃核糖合成路线 （共 36 条）
反应条件
1: Dess-Martin periodane, MgSO4 / CH2Cl2 2: TiCl4, dimethylaminopyridine, Et3N 3: 1.) (TMSO)(TMSN)C(Me), SnCl4; 2.) NH3 / 1.) acetonitrile, reflux, 3 h; 2.) MeOH View Scheme
参考文献
Wolfe; Harry-O'kuru
Tetrahedron Letters, 1995 , vol. 36, # 42 p. 7611 - 7614
反应条件
1: 74 percent / BF3*(C2H5)2O / CH2Cl2 / 0 °C 2: 1.) HMDS, (NH4)2SO4, 2.) SnCl4 / 1.) reflux, overnight, 2.) dichloroethane, reflux, 60 min 3: 80 percent / NH3 / methanol / 48 h / 4 °C View Scheme
参考文献
Chavis, C.; Dumont, F.; Wightman, R. H.; Ziegler, J. C.; Imbach, J. L.
Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 202 - 206
反应条件
1: 92 percent / 2,6-lutidine / CH2Cl2 / 10 h / 20 °C
2: 83 percent / SnCl4 / acetonitrile / 20 °C
3: 55 percent / 3,6-dimethyl-9-methylcarbazole; Mg(ClO4)2 / propan-2-ol; H2O / Photolysis
4: 80 percent / NH3 / methanol / 100 °C
View Scheme
参考文献
Wang, Zhiwei; Prudhomme, Daniel R.; Buck, Jason R.; Park, Minnie; Rizzo, Carmelo J.
Journal of Organic Chemistry, 2000 , vol. 65, # 19 p. 5969 - 5985
反应条件
pyridine
T=0°C; 3 h;
参考文献
Tann, Chou H.; Brodfuehrer, Paul R.; Brundidge, Steven P.; Sapino, Chester; Howell, Henry G.
Journal of Organic Chemistry, 1985 , vol. 50, # 19 p. 3644 - 3647
反应条件
in pyridine; dichloromethane
T=-10°C; Addition;
参考文献
Rubira, Maria-Jose; Jimeno, Maria-Luisa; Balzarini, Jan; Camarasa, Maria-Jose; Perez-Perez, Maria-Jesus
Tetrahedron, 1998 , vol. 54, # 28 p. 8223 - 8240
反应条件
1: 71 percent / CH2N2, BF3*OEt2 / CH2Cl2 / 0.5 h / 4 °C
2: 68 percent / trimethylsilyl trifluoromethanesulfonate / acetonitrile / 0.5 h / Ambient temperature
3: 98 percent / NH4OH / methanol / 17 h / Ambient temperature
View Scheme
参考文献
Ross; Springer; Vasquez; Andrews; Cook; Acevedo
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 4 p. 765 - 769
