2-氯-3-硝基-5-(三氟甲基)苯甲酸合成路线 （共 2 条）
反应条件
sulfuric acid; nitric acid T=90°C; 1.18333 h;
参考文献
THE UNIVERSITY OF QUEENSLAND; COOPER, Matthew; ZUEGG, Johannes; BECKER, Bernd; TOMISLAV, Karoli
Patent: WO2013/38259 A1, 2013 ;
Location in patent: Page/Page column 12 ;
反应条件
1.1: N,N,N',N,-tetramethylethylenediamine; n-butyllithium / tetrahydrofuran; hexanes / 1 h / -78 °C / Inert atmosphere 1.2: 0.33 h 1.3: pH 1 / Acidic aqueous solution 2.1: nitric acid; sulfuric acid / 1.18 h / 90 °C View Scheme
