1-(1,3-苯并恶唑-2-基)-2,2,2-三氟乙烷酮合成路线 (共 2 条)
反应条件
1: in toluene T=-19°C; 2: With triethylamine in toluene T=-19 - 20°C; Further stages.;
参考文献
Khodakovskiy, Pavel V.; Volochnyuk, Dmitriy M.; Panov, Dmitriy M.; Pervak, Igor I.; Zarudnitskii, Evgenij V.; Shishkin, Oleg V.; Yurchenko, Aleksandr A.; Shivanyuk, Alexander; Tolmachev, Andrey A.
Synthesis, 2008 , # 6 p. 948 - 956
反应条件
1: 1,3-benzoxazole With lithium diisopropyl amide Metallation; 2: ethyl-α,α,α-trifluoroacetate Acetylation;
参考文献
Kawase, Masami; Sakagami, Hiroshi; Kusama, Kaoru; Motohashi, Noboru; Saito, Setsuo
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 21 p. 3113 - 3118