3,4-二氢-2H-苯并[1,4]噁嗪-2-羧酸乙酯合成路线 （共 15 条）
反应条件
potassium carbonate in acetone 20 h; Heating;
参考文献
Touzeau, Frederique; Arrault, Axelle; Guillaumet, Gerald; Scalbert, Elizabeth; Pfeiffer, Bruno; Rettori, Marie-Claire; Renard, Pierre; Merour, Jean-Yves
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1962 - 1979
反应条件
potassium carbonate in acetone 18 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 38, # 1 p. 221 - 225
反应条件
potassium carbonate in water
参考文献
US5719141 A1, ;
US 5719141 A
反应条件
potassium carbonate in acetone 18 h; Heating;
参考文献
Touzeau, Frederique; Arrault, Axelle; Guillaumet, Gerald; Scalbert, Elizabeth; Pfeiffer, Bruno; Rettori, Marie-Claire; Renard, Pierre; Merour, Jean-Yves
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1962 - 1979
反应条件
potassium carbonate in acetone 48 h; Heating;
参考文献
Stefanic, Petra; Turnsek, Katja; Kikelj, Danijel
Tetrahedron, 2003 , vol. 59, # 36 p. 7123 - 7129
反应条件
1: 38 percent / 1) reflux, 1 h, 2) RT, 16 h 2: diborane / tetrahydrofuran / 18 h / Ambient temperature View Scheme
参考文献
JANSSEN PHARMACEUTICA N.V.
Patent: WO2006/24627 A2, 2006 ;
Location in patent: Page/Page column 42 ;
WO 2006/024627 A2
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; 3.5 h;
参考文献
Bourlot, Anne-Sophie; Guillaumet, Gerald; Merour, Jean-Yves
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 1 p. 191 - 196
反应条件
1: NH3 (g) / ethanol / 14 h 2: POCl3 / pyridine / 1) 0 - 5 deg C, 1 h, 2) RT, 3 h View Scheme
参考文献
Butler; Chapleo; Myers; Welbourn
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 1 p. 177 - 181
反应条件
1: 25percent aq. NH3 / 12 h / Heating 2: 68 percent / LiAlH4 / tetrahydrofuran / 36 h / 45 °C View Scheme
参考文献
Bourlot, Anne-Sophie; Sanchez, Isabel; Dureng, Georges; Guillaumet, Gerald; Massingham, Roy; Monteil, Andre; Winslow, Eileen; Pujol, M. Dolors; Merour, Jean-Yves
Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3142 - 3158
