6-氯-3,4-二氢-2H-异喹啉-1-酮合成路线 （共 3 条）
反应条件
1: triethylamine / N,N-dimethyl-formamide / 1 h / 0 - 25 °C 2: trifluorormethanesulfonic acid / 16 h / 0 - 70 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 20 p. 9313 - 9328,16
反应条件
1: triethylamine / dichloromethane / 0.5 h / 0 - 20 °C / |Inert atmosphere 2: polyphosphoric acid / 2 h / 120 °C / |Inert atmosphere View Scheme
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in 1,4-dioxane Inert atmosphereReflux;
参考文献
F. HOFFMANN-LA ROCHE AG; AEBI, Johannes; AMREIN, Kurt; CHEN, Wenming; HORNSPERGER, Benoit; KUHN, Bernd; LIU, Yongfu; MAERKI, Hans P.; MAYWEG, Alexander V.; MOHR, Peter; TAN, Xuefei; WANG, Zhanguo; ZHOU, Mingwei
Patent: WO2013/79452 A1, 2013 ;
Location in patent: Page/Page column 133 ;
