6-氨基-3,4-二氢-2(1H)-喹啉酮合成路线 （共 5 条）
反应条件
Pd/C; hydrogen in methanol
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 16 p. 4606 - 4609
反应条件
1: concentrated sulfuric acid; nitric acid 2: tin; aqueous HCl View Scheme
参考文献
Proceedings of the Imperial Academy (Tokyo), , vol. 15, p. 148,153
Chem. Zentralbl., , vol. 110, # II p. 3089
反应条件
phosphoric acid in water
参考文献
Otsuka Pharmaceutical Co., Ltd.
Patent: US4415572 A1, 1983 ;
反应条件
potassium carbonate in methanol
参考文献
Otsuka Pharmaceutical Co., Ltd.
Patent: US4415572 A1, 1983 ;
反应条件
1: 2.) sodium carbonate / 1.) EtOH, reflux, 8 h; 2.) reflux, 8 h
2: 70 percent / triethylamine / dimethylformamide / 1 h / Ambient temperature
View Scheme
参考文献
Tominaga; Yo; Ogawa; Yamashita; Yabuuchi; Nakagawa
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 6 p. 2100 - 2110
