(S)-2-乙氧基-3-(4-羟基苯基)丙酸乙酯合成路线 （共 15 条）
反应条件
1: sodium octyl mercaptide / 1-methyl-pyrrolidin-2-one / 120 - 170 °C 2: hydrogenchloride; water / ethyl acetate / 5 h / 79 - 80 °C View Scheme
参考文献
Organic Process Research and Development, , vol. 8, # 6 p. 838 - 845
反应条件
1: n-octanethiol; sodium hydroxide; water / toluene; 1-methyl-pyrrolidin-2-one / 19 h / 125 °C 2: hydrogenchloride; water / ethyl acetate / 5 h / 79 - 80 °C View Scheme
参考文献
Organic Process Research and Development, , vol. 8, # 6 p. 838 - 845
反应条件
chloro-trimethyl-silane
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 13 p. 3595 - 3598
反应条件
hydrogenchloride; thionyl chloride 2 h; Heating / reflux;
参考文献
US6362360 B1, ;
Example 2 ;
反应条件
water; sodium hydroxide T=95°C; pH=10.0; Kinetics; pH-valueConcentration;
参考文献
Chan, Lai Chun; Cox, Brian G.; Sinclair, Rhona S.
Organic Process Research and Development, 2008 , vol. 12, # 2 p. 213 - 217
