2-溴-3'-硝基苯乙酮合成路线 (共 50 条)
参考文献
Hill, Richard K.; Nugara, Peter N.; Holt, Elizabeth M.; Holland, Kathleen P.
Journal of Organic Chemistry, 1992 , vol. 57, # 3 p. 1045 - 1047
反应条件
1: acetone / Heating
2: K2CO3 / H2O / Heating
View Scheme
参考文献
Chai, Wenying; Kwok, Annette; Wong, Victoria; Carruthers, Nicholas I.; Wu, Jiejun
Synlett, 2003 , # 13 p. 2086 - 2088
反应条件
ethanol
und Erwaermen des Reaktionsprodukts mit wss.Natriumhydrogencarbonat-Loesung;
参考文献
Buu-Hoi; Khoi
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1950 , vol. 230, p. 967
反应条件
1: sodium tetrahydroborate / Inert atmosphere
2: sodium azide / dichloromethane / 8 h / 20 - 70 °C / Inert atmosphere
3: palladium 10 on activated carbon; hydrogen / methanol / 5 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Heller, Stephen T.; Schultz, Erica E.; Sarpong, Richmond
Angewandte Chemie - International Edition, 2012 , vol. 51, # 33 p. 8304 - 8308
参考文献
Tewari, R. S.; Dubey, A. K.; Gupta, K. C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 8 p. 706 - 707
参考文献
Bahner et al.
Journal of the American Chemical Society, 1951 , vol. 73, p. 3499
参考文献
JANSSEN PHARMACEUTICA N.V.; ARTS, Frank Xavier Jozef Herwig; HEERES, Jan
Patent: WO2006/79642 A1, 2006 ;
Location in patent: Page/Page column 9 ;
反应条件
in acetonitrile
0.5 h; Heating;
参考文献
Raeymaekers,A.H.M. et al.
Journal of Medicinal Chemistry, 1966 , vol. 9, p. 545 - 551
反应条件
water; silver nitrate
参考文献
Evans; Witzemann
Journal of the American Chemical Society, 1911 , vol. 33, p. 1773
参考文献
Evans; Witzemann
Journal of the American Chemical Society, 1911 , vol. 33, p. 1773