sodium carbonate in 1,4-dioxane T=0°C; 24 h;

1: ethyl N-(2-propenyl)glycinate With sodium hydroxide in 1,4-dioxane; methanol; water Hydrolysis; 0.75 h; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium hydroxide in 1,4-dioxane; methanol; water Acylation; pH=8.5 - 9.0; 16 h; Further stages.;

1: N-allylglycine methyl ester With water; sodium hydroxide T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium hydrogencarbonate in 1,4-dioxane; water T=20°C;

sodium hydroxide in 1,4-dioxane Yield given;