potassium carbonate in N,N-dimethyl-formamide T=20°C; 4 h;

sodium hydroxide T=70°C;

1: 85 percent / sodium acetate / ethanol / 3 h / Heating 2: EtONa / ethanol / 1 h / Heating View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: dioxane / 0.08 h / Heating<br />2: dioxane / 2 h / Heating<br /> <br /> &nbsp;

&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102551', constants.ctx, '0')">1,4-dioxane</a> <br />2&nbsp;h;&nbsp;&nbsp;Heating;&nbsp;&nbsp;Yield given;&nbsp;<br /> &nbsp;