2-溴-5-硝基-6-甲基吡啶合成路线 (共 4 条)
反应条件
bromine; phosphorus tribromide
参考文献
Journal of the American Chemical Society, , vol. 77, p. 6053
反应条件
phosphorus oxytribromide in tetrachloroethane, 1,1,2,2- 4 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 5 p. 795 - 798
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=80°C; 5 h;
参考文献
Sanderson, Philip E. J.; Stanton, Matthew G.; Dorsey, Bruce D.; Lyle, Terry A.; McDonough, Colleen; Sanders, William M.; Savage, Kelly L.; Naylor-Olsen, Adel M.; Krueger, Julie A.; Lewis, S. Dale; Lucas, Bobby J.; Lynch, Joseph J.; Yan, Youwei
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 5 p. 795 - 798
反应条件
1.1: (Ph3P)4Pd / dimethylformamide / 5 h / 80 °C 2.1: dimethylformamide / 2 h / 90 °C 2.2: MeOH; 6 M HCl / 10 percent Pd/C / 16 h View Scheme
参考文献
Sanderson, Philip E. J.; Stanton, Matthew G.; Dorsey, Bruce D.; Lyle, Terry A.; McDonough, Colleen; Sanders, William M.; Savage, Kelly L.; Naylor-Olsen, Adel M.; Krueger, Julie A.; Lewis, S. Dale; Lucas, Bobby J.; Lynch, Joseph J.; Yan, Youwei
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 5 p. 795 - 798