4-溴-2-甲基吡啶合成路线

参考文献

VITAE PHARMACEUTICALS, INC.; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; LEFTHERIS, Katerina; ZHUANG, Linghang; TICE, Colin, M.; SINGH, Suresh, B.; YE, Yuanjie; XU, Zhenrong; HIMMELSBACH, Frank; ECKHARDT, Matthias
Patent: WO2011/159760 A1, 2011 ;
Location in patent: Page/Page column 73 ;
WO 2011/159760 A1

22282-99-14-溴-2-甲基吡啶

106877-17-22-甲基-4-(三氟甲基)吡啶

参考文献

Mormino, Michael G.; Fier, Patrick S.; Hartwig, John F.
Organic Letters, 2014 , vol. 16, # 6 p. 1744 - 1747

22282-99-14-溴-2-甲基吡啶

30766-03-14-溴吡啶-2-羧酸

参考文献

CURIS, INC.
Patent: WO2008/57497 A2, 2008 ;
Location in patent: Page/Page column 292-293 ;

22282-99-14-溴-2-甲基吡啶

192642-94-74-溴吡啶-2-乙酸甲酯

参考文献

Klepser, Benjamin M.; Bartlett, Bart M.
Journal of the American Chemical Society, 2014 , vol. 136, # 5 p. 1694 - 1697

22282-99-14-溴-2-甲基吡啶+

1066-54-2三甲基乙炔基硅

30413-56-04-乙炔-2-甲基吡啶

参考文献

Roche Palo Alto LLC
Patent: US2010/56535 A1, 2010 ;
Location in patent: Page/Page column 19 ;

22282-99-14-溴-2-甲基吡啶

865156-50-9(4-溴吡啶-2-基)甲胺

参考文献

Monnard, Fabien W.; Nogueira, Elisa S.; Heinisch, Tillmann; Schirmer, Tilman; Ward, Thomas R.
Chemical Science, 2013 , vol. 4, # 8 p. 3269 - 3274

22282-99-14-溴-2-甲基吡啶+

5419-55-6硼酸三异丙酯

579476-63-42-甲基-4-吡啶硼酸

参考文献

NOVARTIS AG
Patent: WO2009/118292 A1, 2009 ;
Location in patent: Page/Page column 84 ;

22282-99-14-溴-2-甲基吡啶

579476-63-42-甲基-4-吡啶硼酸

参考文献

Molander, Gary A.; Cavalcanti, Livia N.; Garcia-Garcia, Carolina
Journal of Organic Chemistry, 2013 , vol. 78, # 13 p. 6427 - 6439

22282-99-14-溴-2-甲基吡啶+

73183-34-3

660867-80-1

参考文献

F. HOFFMANN-LA ROCHE AG; BAUMANN, Karlheinz; GOETSCHI, Erwin; GREEN, Luke; JOLIDON, Synese; KNUST, Henner; LIMBERG, Anja; LUEBBERS, Thomas; THOMAS, Andrew
Patent: WO2011/92272 A1, 2011 ;
Location in patent: Page/Page column 73 ;
WO 2011/092272 A1

22282-99-14-溴-2-甲基吡啶

1032650-53-5

参考文献

GLAXOSMITHKLINE LLC; BROOKS, Carl; CHEUNG, Mui; EIDAM, Hilary, Schenck; GOODMAN, Krista, B.; HAMMOND, Marlys; HILFIKER, Mark, A.; HOANG, Tram, H.; PATTERSON, Jaclyn, R.; STOY, Patrick; YE, Guosen
Patent: WO2013/12500 A1, 2013 ;
Location in patent: Page/Page column 127 ;
WO 2013/012500 A1