3-氨基-2-噻吩甲酸甲酯合成路线

参考文献

Crespo, Maria I.; Pages, Lluis; Vega, Armando; Segarra, Victor; Lopez, Manel; Domenech, Teresa; Miralpeix, Montserrat; Beleta, Jordi; Ryder, Hamish; Palacios, Jose M.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 21 p. 4021 - 4035

22288-78-43-氨基-2-噻吩甲酸甲酯+

24424-99-5二碳酸二叔丁酯

19228-91-2噻吩-3-氨基甲酸叔丁酯

参考文献

Dominguez-Manzanares, Esteban
Patent: US2006/276532 A1, 2006 ;
Location in patent: Page/Page column 4 ;

22288-78-43-氨基-2-噻吩甲酸甲酯+

98-88-4苯甲酰氯

18678-14-32-苯基噻吩并[3,2-d]嘧啶-4-醇

参考文献

Crespo, Maria I.; Pages, Lluis; Vega, Armando; Segarra, Victor; Lopez, Manel; Domenech, Teresa; Miralpeix, Montserrat; Beleta, Jordi; Ryder, Hamish; Palacios, Jose M.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 21 p. 4021 - 4035

22288-78-43-氨基-2-噻吩甲酸甲酯+

503-38-8氯甲酸三氯甲酯

25712-16-7

参考文献

E. I. du Pont de Nemours and Company
Patent: US6096895 A1, 2000 ;

22288-78-43-氨基-2-噻吩甲酸甲酯+

32315-10-9三光气

25712-16-7

参考文献

Vaisburg, Arkadii; Paquin, Isabelle; Bernstein, Naomy; Frechette, Sylvie; Gaudette, Frederic; Leit, Silvana; Moradei, Oscar; Raeppel, Stephane; Zhou, Nancy; Bouchain, Giliane; Woo, Soon Hyung; Jin, Zhiyun; Gillespie, Jeff; Wang, James; Fournel, Marielle; Yan, Pu Theresa; Trachy-Bourget, Marie-Claude; Robert, Marie-France; Lu, Aihua; Yuk, Jimmy; Rahil, Jubrail; MacLeod, A. Robert; Besterman, Jeffrey M.; Li, Zuomei; Delorme, Daniel
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 24 p. 6729 - 6733

22288-78-43-氨基-2-噻吩甲酸甲酯

25712-16-7

参考文献

Lebedev; Lebedeva; Sheludyakov; Ovcharuk; Kovaleva; Ustinova
Russian Journal of General Chemistry, 2006 , vol. 76, # 1 p. 110 - 115

22288-78-43-氨基-2-噻吩甲酸甲酯

31169-25-27-溴噻吩并[3,2-D]嘧啶-4(1H)-酮

参考文献

HANMI PHARM. CO., LTD.; BANG, Keuk Chan; PARK, Chang Hee; CHOI, Jae Yul; KIM, Seo Hee; HAM, Young Jin
Patent: WO2014/3483 A1, 2014 ;

22288-78-43-氨基-2-噻吩甲酸甲酯

31169-27-47-溴-4-氯噻吩并[3,2-d]嘧啶

参考文献

HANMI PHARM. CO., LTD.; BANG, Keuk Chan; PARK, Chang Hee; CHOI, Jae Yul; KIM, Seo Hee; HAM, Young Jin
Patent: WO2014/3483 A1, 2014 ;

22288-78-43-氨基-2-噻吩甲酸甲酯

86427-02-33-氯噻吩-2-甲酰氯

参考文献

Eller, Gernot A.; Haring, Andreas W.; Datterl, Barbara; Zwettler, Maryam; Holzer, Wolfgang
Heterocycles, 2007 , vol. 71, # 1 p. 87 - 104

22288-78-43-氨基-2-噻吩甲酸甲酯

885618-31-52-氯-4-(4-吗啉)-噻吩并[3,2-d]嘧啶-6-羧醛

参考文献

Zhu, Wufu; Zhai, Xin; Fu, Qiangqiang; Guo, Fei; Bai, Mei; Wang, Jianqiang; Wang, Haiyan; Gong, Ping
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