1: 93 percent / 60 percent HBr / acetic acid / 6 h / Heating 2: 88 percent / CH3COOH, CH3COONa, hydroquinone / H2O / 17 h / 220 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11604118', constants.ctx, '0')">tetrakis(triphenylphosphine) palladium⁽⁰⁾</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '2821785', constants.ctx, '0')">1,3-bis-(diphenylphosphino)propane</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '4933628', constants.ctx, '0')">silver nitrate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '635680', constants.ctx, '0')">acetone</a> <br />T=40&deg;C;&nbsp;P=760.051&nbsp;Torr;&nbsp;24&nbsp;h;&nbsp;&nbsp;AutoclaveInert atmosphere;&nbsp;<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 86 percent / n-BuLi / tetrahydrofuran; hexane / Ambient temperature; 1.) 3 h, 2.) overnight<br />2: 41 percent / Jones reagent / acetone / 5 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 86 percent / n-BuLi / tetrahydrofuran; hexane / Ambient temperature; 1.) 3 h, 2.) overnight<br />2: 41 percent / Jones reagent / acetone / 5 &deg;C<br /> <br /> &nbsp;