1,5-双(2-溴-5-甲氧基苯基)-3-戊酮合成路线 （共 6 条）
反应条件
1: 62 percent / aq. NaOH / ethanol / 2 h / Ambient temperature 2: H2 / Raney Ni / acetone / 24 h / 760 Torr / Ambient temperature 3: Br2, pyridine / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Birman, Vladimir B.; Rheingold, Arnold L.; Lam, Kin-Chung
Tetrahedron Asymmetry, 1999 , vol. 10, # 1 p. 125 - 131
反应条件
1: H2 / Raney Ni / acetone / 24 h / 760 Torr / Ambient temperature 2: Br2, pyridine / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Birman, Vladimir B.; Rheingold, Arnold L.; Lam, Kin-Chung
Tetrahedron Asymmetry, 1999 , vol. 10, # 1 p. 125 - 131
反应条件
pyridine; bromine in dichloromethane 4 h; Ambient temperature; Yield given;
参考文献
Birman, Vladimir B.; Rheingold, Arnold L.; Lam, Kin-Chung
Tetrahedron Asymmetry, 1999 , vol. 10, # 1 p. 125 - 131
反应条件
1: 65 percent / polyphosphoric acid / 5.5 h / 105 °C 2: 93 percent / n-Buli / tetrahydrofuran; hexane / 1 h / -78 °C 3: 85 percent / BBr3 / CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Birman, Vladimir B.; Rheingold, Arnold L.; Lam, Kin-Chung
Tetrahedron Asymmetry, 1999 , vol. 10, # 1 p. 125 - 131
反应条件
1: 65 percent / polyphosphoric acid / 5.5 h / 105 °C 2: 93 percent / n-Buli / tetrahydrofuran; hexane / 1 h / -78 °C 3: 85 percent / BBr3 / CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Birman, Vladimir B.; Rheingold, Arnold L.; Lam, Kin-Chung
Tetrahedron Asymmetry, 1999 , vol. 10, # 1 p. 125 - 131
反应条件
1: 65 percent / polyphosphoric acid / 5.5 h / 105 °C 2: 93 percent / n-Buli / tetrahydrofuran; hexane / 1 h / -78 °C 3: 85 percent / BBr3 / CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Birman, Vladimir B.; Rheingold, Arnold L.; Lam, Kin-Chung
Tetrahedron Asymmetry, 1999 , vol. 10, # 1 p. 125 - 131
