(S)-(+)-1,2-异亚丙基甘油合成路线 （共 82 条）
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane T=22°C; 3 h;
参考文献
Craven, R. John; Lencki, Robert W.
Crystal Growth and Design, 2011 , vol. 11, # 5 p. 1723 - 1732
反应条件
pyridine; tetrachloromethane; triphenylphosphine in benzene Heating;
参考文献
Kawakami, Yuhsuke; Asai, Tamio; Umeyama, Kiyoshi; Yamashita, Yuya
Journal of Organic Chemistry, 1982 , vol. 47, # 18 p. 3581 - 3585
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane T=22°C; 3 h;
参考文献
Craven, R. John; Lencki, Robert W.
Crystal Growth and Design, 2011 , vol. 11, # 5 p. 1723 - 1732
反应条件
in ethylene glycol dimethyl ether; water
参考文献
G. D. Searle and Co.
Patent: US4567189 A1, 1986 ;
反应条件
pyridine T=4 - 20°C; 28 h;
参考文献
El-Essawy, Farag A.; Khattab, Ahmed F.
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 3 p. 311 - 316
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane T=22°C; 3 h;
参考文献
Craven, R. John; Lencki, Robert W.
Crystal Growth and Design, 2011 , vol. 11, # 5 p. 1723 - 1732
反应条件
1: 69.4 percent / KOH, KMnO4 / H2O / 3 h / 40 °C 2: 76 percent / 4.19 M HCl View Scheme
参考文献
Dumont, Raymond; Pfander, Hanspeter
Helvetica Chimica Acta, 1983 , vol. 66, # 3 p. 814 - 823
反应条件
1: DMSO; oxalyl chloride; Et3N / CH2Cl2 / -78 - 20 °C 2: CH2Cl2 / 20 °C View Scheme
参考文献
Schomaker, Jennifer M.; Pulgam, Veera Reddy; Borhan, Babak
Journal of the American Chemical Society, 2004 , vol. 126, # 42 p. 13600 - 13601
反应条件
manganese(IV) oxide in toluene Oxidation; Wittig reaction; 20 h; Heating; Title compound not separated from byproducts;
参考文献
Blackburn, Leonie; Wei, Xudong; Taylor, Richard J. K.
Chemical Communications, 1999 , # 14 p. 1337 - 1338
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-78 - 20°C; Swern oxidation; Inert atmosphere;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 49, # 2 p. 260 - 263
