2-(3-溴-4-甲氧基苯基)-1,3-二氧戊环合成路线 （共 8 条）
反应条件
in dichloromethane T=50°C; 0.0833333 h; Microwave irradiationSealed tube;
参考文献
Ramanathan, Mani; Hou, Duen-Ren
Arkivoc, 2013 , vol. 2013, # 3 p. 98 - 108
反应条件
in dichloromethane T=50°C; 0.0833333 h; Microwave irradiationSealed tube;
参考文献
Ramanathan, Mani; Hou, Duen-Ren
Arkivoc, 2013 , vol. 2013, # 3 p. 98 - 108
反应条件
potassium carbonate in acetone
T=20°C;
参考文献
PURDUE RESEARCH FOUNDATION
Patent: WO2008/76767 A1, 2008 ;
Location in patent: Page/Page column 18; 30 ;
反应条件
in water; ethylene glycol; toluene
参考文献
Sanofi-Synthelabo
Patent: US6673790 B1, 2004 ;
US 6673790 B1
反应条件
toluene-4-sulfonic acid in benzene
6 h; Heating;
参考文献
Anson, Christopher E.; Creaser, Colin S.; Malkov, Andrej V.; Mojovic, Ljubica; Stephenson, G. Richard
Journal of Organometallic Chemistry, 2003 , vol. 668, # 1-2 p. 101 - 122
反应条件
1: 95 percent / p-TsOH / toluene / 24 h / Heating
2: 91 percent / K2CO3 / acetone / 20 °C
View Scheme
参考文献
Maiti, Arup; Cuendet, Muriel; Croy, Vicki L.; Endringer, Denise C.; Pezzuto, John M.; Cushman, Mark
Journal of Medicinal Chemistry, 2007 , vol. 50, # 12 p. 2799 - 2806
反应条件
Multistep reaction.;
参考文献
Maiti, Arup; Cuendet, Muriel; Croy, Vicki L.; Endringer, Denise C.; Pezzuto, John M.; Cushman, Mark
Journal of Medicinal Chemistry, 2007 , vol. 50, # 12 p. 2799 - 2806
反应条件
tetrakis(triphenylphosphine) palladium(0)
T=100°C; Product distribution / selectivity;
参考文献
PURDUE RESEARCH FOUNDATION
Patent: WO2008/76767 A1, 2008 ;
Location in patent: Page/Page column 19 ;
