hydrazine hydrate in ethanol 1 h; Heating;

potassium tert-butylate in tetrahydrofuran T=0 - 20°C; 2 h; Product distribution / selectivity;

1: {4,5-dimethoxy-2-[1-(2-methyl-[1,3]dioxolan-2-yl)propyl]phenyl}(3,4-dimethoxyphenyl)methanone With hydrogenchloride; acetic acid in water T=20°C; 1 h; 2: in methanol; water 0.5 h; Reflux; 3: hydrazine hydrate in methanol; water T=20°C; 1.5 h;

hydrazine in methanol T=20 - 40°C; Product distribution / selectivity;

1: With cesium fluoride in acetonitrile T=60°C; 10 h; 2: With hydrazine hydrate in ethanol T=20°C; 16 h;

1: 48 percent / chromium trioxide, 35percent H2SO4 / acetone; H2O / 2 h / Ambient temperature 2: 60 percent / hydrazin hydrate 98percent / ethanol / 1 h / Heating View Scheme

1: 92 percent / HCl gas / dioxane / 1 h / Heating 2: 48 percent / chromium trioxide, 35percent H2SO4 / acetone; H2O / 2 h / Ambient temperature 3: 60 percent / hydrazin hydrate 98percent / ethanol / 1 h / Heating View Scheme

1: 92 percent / HCl gas / dioxane / 1 h / Heating 2: 48 percent / chromium trioxide, 35percent H2SO4 / acetone; H2O / 2 h / Ambient temperature 3: 60 percent / hydrazin hydrate 98percent / ethanol / 1 h / Heating View Scheme

1.1: N-benzyl-trimethylammonium hydroxide; sodium hydroxide / methanol / 6.25 h / 10 - 60 °C 2.1: N-bromosuccinmide / ethyl acetate / 3 h / 0 - 5 °C 3.1: toluene-4-sulfonic acid / toluene / 24 h / |Dean-Stark; |Reflux 4.1: n-hexyl lithium / toluene; hexane / 0.5 h / -40 °C 4.2: 1.5 h / -40 - 0 °C 5.1: hydrogenchloride; acetic acid / water / 1 h / 20 °C 5.2: 0.5 h / |Reflux 5.3: 1.5 h / 20 °C View Scheme

1.1: toluene-4-sulfonic acid / toluene / 24 h / |Dean-Stark; |Reflux 2.1: n-hexyl lithium / toluene; hexane / 0.5 h / -40 °C 2.2: 1.5 h / -40 - 0 °C 3.1: hydrogenchloride; acetic acid / water / 1 h / 20 °C 3.2: 0.5 h / |Reflux 3.3: 1.5 h / 20 °C View Scheme