(R)-(+)-2-(二苯甲基)吡咯烷合成路线 (共 9 条)
反应条件
hydrogen; palladium on activated charcoal in methanol 48 h; Ambient temperature;
参考文献
Bailey, David J.; O'Hagan, David; Tavasli, Mustafa
Tetrahedron Asymmetry, 1997 , vol. 8, # 1 p. 149 - 153
反应条件
hydrogen; palladium on activated charcoal in ethanol 3 h; Heating;
参考文献
Enders, Dieter; Kipphardt, Helmut; Gerdes, Peter; Brena-Valle, Leonardo J.; Bhushan, Vidya
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 8-9 p. 691 - 704
反应条件
1: 82 percent / tetrahydrofuran / 3 h / Heating 2: 86 percent / H2 / Pd/C / methanol / 48 h / Ambient temperature View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 8, # 1 p. 149 - 153
反应条件
1: 82 percent / tetrahydrofuran / 3 h / Heating 2: 86 percent / H2 / Pd/C / methanol / 48 h / Ambient temperature View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 8, # 1 p. 149 - 153
反应条件
1: 75 percent / diethyl ether / 2 h / Heating 2: 72 percent / Li, NH3 / diethyl ether; tetrahydrofuran / 3 h / -45 °C 3: 91 percent / H2 / 10 percent Pd/C / ethanol / 3 h / Heating View Scheme
参考文献
Bulletin des Societes Chimiques Belges, , vol. 97, # 8-9 p. 691 - 704
反应条件
1: 72 percent / Li, NH3 / diethyl ether; tetrahydrofuran / 3 h / -45 °C 2: 91 percent / H2 / 10 percent Pd/C / ethanol / 3 h / Heating View Scheme
参考文献
Bulletin des Societes Chimiques Belges, , vol. 97, # 8-9 p. 691 - 704
反应条件
1: thionylchloride / -30 deg C to Rt, reflux, 1 h 2: triethylamine / ethanol / 4 h / Heating 3: 75 percent / diethyl ether / 2 h / Heating 4: 72 percent / Li, NH3 / diethyl ether; tetrahydrofuran / 3 h / -45 °C 5: 91 percent / H2 / 10 percent Pd/C / ethanol / 3 h / Heating View Scheme
参考文献
Bulletin des Societes Chimiques Belges, , vol. 97, # 8-9 p. 691 - 704
反应条件
1: triethylamine / ethanol / 4 h / Heating 2: 75 percent / diethyl ether / 2 h / Heating 3: 72 percent / Li, NH3 / diethyl ether; tetrahydrofuran / 3 h / -45 °C 4: 91 percent / H2 / 10 percent Pd/C / ethanol / 3 h / Heating View Scheme
参考文献
Bulletin des Societes Chimiques Belges, , vol. 97, # 8-9 p. 691 - 704
参考文献
WISCONSIN ALUMNI RESEARCH FOUNDATION
Patent: WO2007/112358 A1, 2007 ;
Location in patent: Page/Page column 39 ;