N-环己基-4-溴苯甲酰胺合成路线 (共 6 条)
反应条件
indium in water; acetonitrile T=20°C; 3 h;
参考文献
Cho, Dae Hyan; Jang, Doo Ok
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2285 - 2287
反应条件
magnetite nanoparticle-supported sulfonic acid in neat (no solvent) T=90°C; Ritter Amidation; 5 h;
参考文献
Green Chemistry, , vol. 15, # 7 p. 1895 - 1899
反应条件
dipotassium peroxodisulfate; palladium diacetate; silver nitrate in water; dimethyl sulfoxide; acetonitrile T=70°C; 0.166667 h;
参考文献
Li, Mingzong; Wang, Cong; Fang, Ping; Ge, Haibo
Chemical Communications, 2011 , vol. 47, # 23 p. 6587 - 6589
反应条件
copper(l) iodide; di-tert-butyl peroxide; 4,7-Dimethoxy-1,10-phenanthroline in benzene T=100°C; 24 h; Inert atmosphere;
参考文献
Tran, Ba L.; Li, Bijie; Driess, Matthias; Hartwig, John F.
Journal of the American Chemical Society, 2014 , vol. 136, # 6 p. 2555 - 2563
反应条件
1: trichloroacetonitrile; triphenylphosphine / CH2Cl2 / 2 h / 20 °C 2: triethylamine / CH2Cl2 / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 40, # 29 p. 5323 - 5326
反应条件
1: N-cyclohexyl-4-bromobenzamide With 2-fluoro-pyridine; trifluoromethylsulfonic anhydride in dichloromethane T=-78 - 0°C; Inert atmosphere; 2: ethylmagnesium bromide in dichloromethane T=-78°C; 0.416667 h; Inert atmosphere; 3: With hydrogenchloride; water in tetrahydrofuran; dichloromethane T=65°C; 2 h; Inert atmosphere; chemoselective reaction;
参考文献
Bechara, William S.; Pelletier, Guillaume; Charette, Andre B.
Nature Chemistry, 2012 , vol. 4, # 3 p. 228 - 234