2,3-二氯-5-硝基-1,4-萘醌合成路线 （共 16 条）
参考文献
Fries; Pense; Peeters
Chemische Berichte, 1928 , vol. 61, p. 1399
反应条件
1: methanol / 1 h / Heating
2: H2 / 10percent Pd/C / tetrahydrofuran / 4 h / 760 Torr
3: pyridine, DMAP / tetrahydrofuran / 1 h
View Scheme
参考文献
Jones, Gordon H.; Venuti, Michael C.; Young, John M.; Murthy, D.V. Krishna; Loe, Brad E.; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1504 - 1511
反应条件
1: With 2,6-di-tert-butyl-pyridine; Rink amide resin plug format in dichloromethane
T=25°C; 2 h;
2: With trifluoroacetic acid in dichloromethane
T=25°C; 0.5 h; Title compound not separated from byproducts;
参考文献
Blackburn, Christopher
Tetrahedron Letters, 2005 , vol. 46, # 9 p. 1405 - 1409
反应条件
sodium methylate; acetic acid in tetrahydrofuran
参考文献
Syntex (U.S.A.) Inc.
Patent: US4229478 A1, 1980 ;
反应条件
in methanol
1 h; Heating;
参考文献
Jones, Gordon H.; Venuti, Michael C.; Young, John M.; Murthy, D.V. Krishna; Loe, Brad E.; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1504 - 1511
参考文献
Sartori
Journal of Organic Chemistry, 1959 , vol. 24, p. 1756,1758
