3-甲基-2-苯并呋喃羧酸乙酯合成路线 （共 8 条）
反应条件
sulfuric acid T=-10°C; 1 h;
参考文献
Bedford, Simon B.; Begley, Michael J.; Cornwall, Philip; Foreman, Joel P.; Knight, David W.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 23 p. 2827 - 2832
反应条件
potassium hydroxide in 1,4-dioxane T=60°C; 6 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 29, # 2 p. 423 - 429
反应条件
potassium carbonate T=80 - 160°C; 3.5 h; Inert atmosphereNeat (no solvent);
参考文献
Yang, Li; Lei, Hua; Mi, Cheng-Gen; Liu, Huan; Zhou, Tian; Zhao, Ying-Lan; Lai, Xiao-Yun; Li, Zi-Cheng; Song, Hang; Huang, Wen-Cai
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5389 - 5392
反应条件
sodium ethanolate in ethanol 10 h; Heating;
参考文献
Tseng, Pen-Wen; Yeh, Su-Wen; Chou, Chin-Hsing
Journal of Organic Chemistry, 2008 , vol. 73, # 9 p. 3481 - 3485
反应条件
phenolated sodium unter Abkuehlen in konz. Schwefelsaeure loesen;
参考文献
Chemische Berichte, , vol. 19, p. 1292
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane 24 h; Reflux;
参考文献
SCHERING CORPORATION; TING, Pauline, C.; LEE, Joe, F.; ASLANIAN, Robert, G.
Patent: WO2011/31628 A1, 2011 ;
Location in patent: Page/Page column 65 ;
WO 2011/031628 A1
反应条件
potassium hydroxide in methanol 24 h; Ambient temperature;
参考文献
Bedford, Simon B.; Begley, Michael J.; Cornwall, Philip; Foreman, Joel P.; Knight, David W.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 23 p. 2827 - 2832
反应条件
1: dibenzoyl peroxide; N-bromosuccinmide / tetrachloromethane / 24 h / Reflux
2: trimethylamine-N-oxide / N,N-dimethyl-formamide / 6 h / 20 °C
View Scheme
参考文献
SCHERING CORPORATION; TING, Pauline, C.; LEE, Joe, F.; ASLANIAN, Robert, G.
Patent: WO2011/31628 A1, 2011 ;
WO 2011/031628 A1
