反应条件
1: NH2OH*HCl, Na2SO4, conc. HCl / dioxane; H2O / 0.75 h / Heating 2: 1.) conc. H2SO4, 2.) 30percent aq. H2O2, 1 N aq. NaOH / 1.) 80 deg C, 10 min, 2.) RT 3: diethyl ether View Scheme
参考文献
Rowley, Michael; Leeson, Paul D.; Stevenson, Graeme I.; Moseley, Angela M.; Stansfield, Ian; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 22 p. 3386 - 3396