1-甲基-3-苯基丙胺合成路线 （共 111 条）
反应条件
coated protease in 3-methyl pentan-3-ol T=21°C; 1.5 h; Resolution of racemateEnzymatic reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 354, # 9 p. 1759 - 1764
反应条件
transaminase ATA-113; pyridoxal 5'-phosphate; sodium 2-oxopropanoate T=30°C; pH=7.0; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 14 p. 2289 - 2292
反应条件
immobilized Properase 1600L in 3-methyl pentan-3-ol T=21°C; 1 h; Enzymatic reaction; optical yield given as percent eediastereoselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 24 p. 2823 - 2834
反应条件
immobilized Properase 1600L in 3-methyl pentan-3-ol T=21°C; 0.666667 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 24 p. 2823 - 2834
反应条件
immobilized alkaline protease in 3-methyl pentan-3-ol T=21°C; 0.166667 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 24 p. 2823 - 2834
反应条件
immobilized alkaline protease in 3-methyl pentan-3-ol T=21°C; 3 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 24 p. 2823 - 2834
反应条件
Candida antarctica lipase B T=28°C; 4 h;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 12 p. 1315 - 1320
反应条件
(S)-selective ω-transaminase from Ochrobactrum anthropi; L-threonine deaminase from Escherichia coli; pyridoxal 5'-phosphate T=37°C; pH=7.5; 5 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Green Chemistry, , vol. 14, # 8 p. 2137 - 2140
反应条件
(S)-selective ω-transaminase from Ochrobactrum anthropi; L-threonine deaminase from Escherichia coli; pyridoxal 5'-phosphate T=37°C; pH=7.5; 5 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Malik, M. Shaheer; Park, Eul-Soo; Shin, Jong-Shik
Green Chemistry, 2012 , vol. 14, # 8 p. 2137 - 2140
反应条件
hydrogenchloride in dichloromethane; water
参考文献
Nugent, Thomas C.; Negru, Daniela E.; El-Shazly, Mohamed; Hu, Dan; Sadiq, Abdul; Bibi, Ahtaram; Umar, M. Naveed
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 2085 - 2092
