1-甲基-3-苯基丙胺合成路线 （共 111 条）
反应条件
supported Candida antartica lipase B in tert-butyl methyl ether T=38 - 40°C; 2.5 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Poulhes, Florent; Vanthuyne, Nicolas; Bertrand, Michele P.; Gastaldi, Stephane; Gil, Gerard
Journal of Organic Chemistry, 2011 , vol. 76, # 17 p. 7281 - 7286
反应条件
transaminase ATA-117; pyridoxal 5'-phosphate; sodium 2-oxopropanoate T=30°C; pH=7.0; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
Koszelewski, Dominik; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2289 - 2292
反应条件
immobilized alkaline protease in 3-methyl pentan-3-ol T=21°C; 0.666667 h; Enzymatic reaction; optical yield given as percent eediastereoselective reaction;
参考文献
Bottalla, Anne-Lise; Queyroy, Severine; Azzi-Schue, Nadia; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Tetrahedron Asymmetry, 2009 , vol. 20, # 24 p. 2823 - 2834
反应条件
immobilized Properase 1600L in 3-methyl pentan-3-ol T=21°C; 0.666667 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Bottalla, Anne-Lise; Queyroy, Severine; Azzi-Schue, Nadia; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Tetrahedron Asymmetry, 2009 , vol. 20, # 24 p. 2823 - 2834
反应条件
immobilized Properase 1600L in 3-methyl pentan-3-ol T=21°C; 1 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Bottalla, Anne-Lise; Queyroy, Severine; Azzi-Schue, Nadia; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Tetrahedron Asymmetry, 2009 , vol. 20, # 24 p. 2823 - 2834
反应条件
coated protease in 3-methyl pentan-3-ol T=21°C; 0.666667 h; Resolution of racemateEnzymatic reaction;
参考文献
Queyroy, Severine; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1759 - 1764
反应条件
coated protease in 3-methyl pentan-3-ol T=21°C; 1.5 h; Resolution of racemateEnzymatic reaction;
参考文献
Queyroy, Severine; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1759 - 1764
反应条件
transaminase ATA-113; pyridoxal 5'-phosphate; sodium 2-oxopropanoate T=30°C; pH=7.0; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
Koszelewski, Dominik; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2289 - 2292
反应条件
immobilized Properase 1600L in 3-methyl pentan-3-ol T=21°C; 1 h; Enzymatic reaction; optical yield given as percent eediastereoselective reaction;
参考文献
Bottalla, Anne-Lise; Queyroy, Severine; Azzi-Schue, Nadia; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Tetrahedron Asymmetry, 2009 , vol. 20, # 24 p. 2823 - 2834
反应条件
immobilized Properase 1600L in 3-methyl pentan-3-ol T=21°C; 0.666667 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Bottalla, Anne-Lise; Queyroy, Severine; Azzi-Schue, Nadia; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Tetrahedron Asymmetry, 2009 , vol. 20, # 24 p. 2823 - 2834
