1: With N-methyl-pyrrolidine; chloro-trimethyl-silane in acetonitrile T=20°C; 1 h; 2: With trifluoroacetic anhydride in acetonitrile T=0°C; 0.0833333 h; 3: With 4-nitro-phenol; anhydrous sodium hydrogen carbonate; ammonia; water more than 3 stages;

chloro-trimethyl-silane; ammonia; trifluoroacetic anhydride in 1,4-dioxane; ethanol; acetonitrile

1: 91 percent / aluminium / 48 h / Heating 2: 1-methylpyrrolidine / acetonitrile / 1 h / 20 °C 3: acetonitrile / 0.58 h / 0 °C 4: acetonitrile / 3 h / 0 °C 5: 5.07 g / conc. aq. NH3 / dioxane / 24 h / 55 °C View Scheme

1: 11.31 g / diphenyl carbonate; sodium hydrogen carbonate / N,N-dimethyl-acetamide / 5 h / 100 °C 2: 91 percent / aluminium / 48 h / Heating 3: 1-methylpyrrolidine / acetonitrile / 1 h / 20 °C 4: acetonitrile / 0.58 h / 0 °C 5: acetonitrile / 3 h / 0 °C 6: 5.07 g / conc. aq. NH3 / dioxane / 24 h / 55 °C View Scheme