8-甲基-1H-嘌呤-6-胺合成路线 (共 5 条)
参考文献
Young, Rodney C.; Jones, Martin; Milliner, Kevin J.; Rana, Kishore K.; Ward, John G.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2073 - 2080
反应条件
Dowex 50WX8 (H(+)) in ethanol 1 h; Heating;
参考文献
Hocek, Michal; Hockova, Dana; Dvorakova, Hana
Synthesis, 2004 , # 6 p. 889 - 894
反应条件
1: 37 percent / Fe(acac)3; NMP / tetrahydrofuran / 8 h / 20 °C 2: 59 percent / NH3 / ethanol / 80 °C 3: 89 percent / aq. Dowex 50WX8 (H(+)) / ethanol / 1 h / Heating View Scheme
参考文献
Hocek, Michal; Hockova, Dana; Dvorakova, Hana
Synthesis, 2004 , # 6 p. 889 - 894
反应条件
1: 59 percent / NH3 / ethanol / 80 °C 2: 89 percent / aq. Dowex 50WX8 (H(+)) / ethanol / 1 h / Heating View Scheme
参考文献
Hocek, Michal; Hockova, Dana; Dvorakova, Hana
Synthesis, 2004 , # 6 p. 889 - 894
反应条件
sodium hydroxide in water T=90.1°C; alkalyne hydrolysis of 6-substituted 9-(1-ethoxyethyl)purines, effect of substituent, formation of intermediates; Product distributionRate constant;
参考文献
Loennberg, Harri; Lehikoinen, Pertti; Neuvonen, Kari
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 10 p. 707 - 712