1: palladium on activated charcoal; hydrogen / methanol 2: 4-acetylamino 2,2,6,6-tetramethylpiperidin-N-oxyl; oxygen; nitric acid; hydrogenchloride / water; acetonitrile / 24 h / 45 °C / |High pressure; |Sealed tube View Scheme

1: palladium on activated charcoal; hydrogen / methanol 2: 4-acetylamino 2,2,6,6-tetramethylpiperidin-N-oxyl; oxygen; nitric acid; hydrogenchloride / water; acetonitrile / 24 h / 45 °C / |High pressure; |Sealed tube 3: potassium carbonate / N,N-dimethyl-formamide / 72 h / 20 °C View Scheme

1: palladium on activated charcoal; hydrogen / methanol 2: 4-acetylamino 2,2,6,6-tetramethylpiperidin-N-oxyl; oxygen; nitric acid; hydrogenchloride / water; acetonitrile / 24 h / 45 °C / |High pressure; |Sealed tube View Scheme

1: palladium on activated charcoal; hydrogen / methanol 2: 4-acetylamino 2,2,6,6-tetramethylpiperidin-N-oxyl; oxygen; nitric acid; hydrogenchloride / water; acetonitrile / 24 h / 45 °C / |High pressure; |Sealed tube View Scheme