1: 4-Methylpyridine With lithium diisopropyl amide in tetrahydrofuran; hexane T=-10°C; 0.333333 h; 2: 1-(3-chlorobenzoyl)-2-methylaziridine in tetrahydrofuran; hexane T=-78°C; 1 h;

1: tert-Butyl N-(4-methyl-pyridin-2-yl)carbamate With n-butyllithium in tetrahydrofuran; hexane T=0°C; 0.5 h; 2: 1-(3-chlorobenzoyl)-2-methylaziridine in tetrahydrofuran; hexane T=-78 - 20°C;

1.1: BuLi / tetrahydrofuran; hexane / 0.5 h / 0 °C 1.2: 78 percent / tetrahydrofuran; hexane / -78 - 20 °C 2.1: 64 percent / Br2; AcOH / 3 h / 80 °C 3.1: 81 percent / dimethylformamide / 14 h / 20 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342940', constants.ctx, '0')">sodium hydroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1696894', constants.ctx, '0')">diethyl ether</a> <br />T=0&deg;C;&nbsp;<br /> &nbsp;