6-氟-1,2,3,4-四氢异喹啉合成路线 (共 2 条)
反应条件
1: With diborane in tetrahydrofuran T=0°C; 18 h; Heating / reflux; 2: With water in tetrahydrofuran T=20°C;
参考文献
US2008/139610 A1, ;
Page/Page column 21 ;
US 20080139610 A1
反应条件
1: methanesulfonic acid; sodium azide / Petroleum ether; dichloromethane; ethyl acetate 2: methanol; hydrogenchloride / |liquid HCl View Scheme