(2-硝基苯基)苯基-甲酮合成路线 （共 48 条）
反应条件
potassium fluoride in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=80°C; 6 h;
参考文献
Effenberger, Franz; Spiegler, Wolfgang
Chemische Berichte, 1985 , vol. 118, # 9 p. 3900 - 3914
反应条件
periodic acid
T=20°C; 0.333333 h;
参考文献
Li, Zheng; Ding, Run-Bo; Xing, Yu-Lin; Shi, Sheng-Yi
Synthetic Communications, 2005 , vol. 35, # 19 p. 2515 - 2520
反应条件
1.1: LDA; HMPA / heptane; tetrahydrofuran; ethylbenzene / 0.5 h / -78 °C
1.2: 37 percent / HMPA / heptane; tetrahydrofuran; ethylbenzene / 0.17 h / -78 °C
2.1: 78 percent / KOH / ethanol / 20 °C
3.1: 90 percent / O2; pivalaldehyde; substituted o-phenylenediamine Co(III) complex / acetonitrile
View Scheme
参考文献
Barroso, Santiago; Blay, Gonzalo; Cardona, Luz; Fernandez, Isabel; Garcia, Begona; Pedro, Jose R.
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6821 - 6829
反应条件
1: 78 percent / KOH / ethanol / 20 °C
2: 90 percent / O2; pivalaldehyde; substituted o-phenylenediamine Co(III) complex / acetonitrile
View Scheme
参考文献
Barroso, Santiago; Blay, Gonzalo; Cardona, Luz; Fernandez, Isabel; Garcia, Begona; Pedro, Jose R.
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6821 - 6829
反应条件
potassium tert-butylate in N,N-dimethyl-formamide
T=100°C; 8 h;
参考文献
Effenberger, Franz; Spiegler, Wolfgang
Chemische Berichte, 1985 , vol. 118, # 9 p. 3872 - 3899
反应条件
KOC(O)Ph in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=100°C; 24 h; further catalysts: KF, Et4NF*2H2O;
参考文献
Effenberger, Franz; Spiegler, Wolfgang
Chemische Berichte, 1985 , vol. 118, # 9 p. 3900 - 3914
反应条件
1: 80 percent / KOtBu / dimethylformamide / 1 h / Ambient temperature; further catalysts: MeCO2K, KF, CsF, Et4NF*2H2O, MeCO2NBu4
2: 27 percent Chromat. / KOtBu / dimethylformamide / 8 h / 100 °C
View Scheme
参考文献
Effenberger, Franz; Spiegler, Wolfgang
Chemische Berichte, 1985 , vol. 118, # 9 p. 3872 - 3899
反应条件
1: 80 percent / KOtBu / dimethylformamide / 1 h / Ambient temperature; further catalysts: MeCO2K, KF, CsF, Et4NF*2H2O, MeCO2NBu4
2: 27 percent Chromat. / KOtBu / dimethylformamide / 8 h / 100 °C
View Scheme
参考文献
Effenberger, Franz; Spiegler, Wolfgang
Chemische Berichte, 1985 , vol. 118, # 9 p. 3872 - 3899
反应条件
1.1: phenyl-magnesium chloride / tetrahydrofuran / 0.5 h / -40 °C / |Inert atmosphere
1.2: 0.5 h / -40 °C / |Inert atmosphere
2.1: Dess-Martin periodane / dichloromethane / 5 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Storz, Michael P.; Maurer, Christine K.; Zimmer, Christina; Wagner, Nathalie; Brengel, Christian; De Jong, Johannes C.; Lucas, Simon; Muesken, Mathias; Haeussler, Susanne; Steinbach, Anke; Hartmann, Rolf W.
Journal of the American Chemical Society, 2012 , vol. 134, # 39 p. 16143 - 16146
反应条件
iron(III) chloride; tetrachloroethane, 1,1,2,2-
T=45 - 50°C;
参考文献
Boetius; Roemisch
Chemische Berichte, 1935 , vol. 68, p. 1924,1931
