3-氟-4-(吗啉基)苯基异氰酸酯合成路线 （共 4 条）
反应条件
1.1: tris(n-butyl)phosphine oxide; lithium bromide / o-xylene / 1 h / Reflux 2.1: hydrogenchloride; water / 0.25 h / 20 °C 2.2: pH 8 - 9 View Scheme
参考文献
Zhang, Xingxian; Zhao, Chengfeng; Gu, Yue
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 5 p. 1143 - 1146,4
反应条件
tris(n-butyl)phosphine oxide; lithium bromide in o-xylene
参考文献
INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION; MCCARTHY, James, R.
Patent: WO2011/137222 A1, 2011 ;
Location in patent: Example 2 ;
反应条件
1.1: tris(n-butyl)phosphine oxide; lithium bromide / o-xylene / 1 h / Reflux 2.1: hydrogenchloride; water / 0.25 h / 20 °C 2.2: pH 8 - 9 3.1: dichloromethane; water / 1 h / 20 °C 3.2: pH 9 / cooling with ice View Scheme
参考文献
Zhang, Xingxian; Zhao, Chengfeng; Gu, Yue
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 5 p. 1143 - 1146,4
反应条件
1: MgI2 etherate / neat (no solvent) / 20 - 65 °C 2: sodium azide / N,N-dimethyl-formamide / 12 h / 85 °C View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 49, # 5 p. 1143 - 1146,4
