(R)-2-氨基-3-邻甲苯丙酸乙酯合成路线 (共 12 条)
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; n-butyllithium; diisopropylamine in tetrahydrofuran; hexane
T=-78°C; stereoselectivity, various substrates; Product distribution;
参考文献
Antonov, Dmitri Yu.; Belokon, Yuri N.; Ikonnikov, Nikolai S.; Orlova, Svetlana A.; Pisarevsky, Aleksander P.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 14 p. 1873 - 1880
反应条件
(i) aq. HCl, (ii) /BRN= 1718733/, SOCl2; Multistep reaction;
参考文献
Terashima,S.; Yamada,S.-I.
Chemical and Pharmaceutical Bulletin, 1968 , vol. 16, # 10 p. 1953 - 1971