3-(4-甲氧基苯基)-丙腈合成路线 （共 33 条）
反应条件
N,N,N',N,-tetramethylethylenediamine; anhydrous iron chloride in tetrahydrofuran T=50°C; 0.5 h;
参考文献
Japan Science and Technology Agency
Patent: EP1724248 A1, 2006 ;
Location in patent: Page/Page column 27-29 ;
反应条件
CuF(PPh3)3*2MeOH; bis[2-(diphenylphosphino)phenyl] ether; tert-butyl alcohol in toluene T=25°C; 3.5 h; Inert atmosphere; chemoselective reaction;
参考文献
Zheng, Ai-Jun; Shan, Feng-Jun; Li, Zheng-Ning; Li, Zeng-Chang; Jiang, Lan
Chemical Papers, 2013 , vol. 67, # 10 p. 1271 - 1276
反应条件
[(1,5-cyclooctadiene)Ir(μ2-OH)]2; potassium tert-butylate; triphenylphosphine in 1,4-dioxane T=130°C; 15 h; Inert atmosphere;
参考文献
Sawaguchi, Takuya; Obora, Yasushi
Chemistry Letters, 2011 , vol. 40, # 9 p. 1055 - 1057
反应条件
NiCl2((PPh3)P)2; BFBED; iron; potassium iodide in N,N-dimethyl acetamide; toluene T=90°C; 24 h; Schlenk techniqueSealed tubeInert atmosphere;
参考文献
Meng, Jing-Jing; Gao, Min; Dong, Min; Wei, Yu-Ping; Zhang, Wen-Qin
Tetrahedron Letters, 2014 , vol. 55, # 13 p. 2107 - 2109
反应条件
anhydrous ammonium carbonate; diphosphorous tetraiodide in carbon disulfide T=20°C; 7 h;
参考文献
Telvekar, Vikas N.; Rane, Rajesh A.
Tetrahedron Letters, 2007 , vol. 48, # 34 p. 6051 - 6053
反应条件
ammonium hydroxide T=25°C; 7 h;
参考文献
Telvekar, Vikas N.; Rane, Rajesh A.; Namjoshi, Tejal V.
Synthetic Communications, 2010 , vol. 40, # 4 p. 494 - 497
反应条件
1: Bu4NCl; NaHCO3 / Pd(OAc)2 / dimethylformamide / 40 °C 2: Mg / methanol / 20 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 18 p. 2704 - 2707
反应条件
Lindlar catalyst; potassium carbonate in water; N,N-dimethyl-formamide T=110°C; 24 h; optical yield given as percent dechemoselective reaction;
参考文献
Senra, Jaqueline D.; Malta, Luiz Fernando B.; Souza, Andrea Luzia F.; Aguiar, Lucia C. S.; Antunesa
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 16 p. 2551 - 2558
反应条件
samarium diiodide in tetrahydrofuran; methanol T=60°C; Reduction; desulfonylation; 4.5 h;
参考文献
Guo, Hongyun; Zhang, Yongmin
Synthetic Communications, 2000 , vol. 30, # 11 p. 1879 - 1885
反应条件
Ru(1-iPr-3-μ-CHMeCH2-4,5-Me2-imidazol-2-yl)(PPh3)2(CO)H in toluene T=70°C; indirect Wittig reaction; 2 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 129, # 7 p. 1987 - 1995
