1,3-二甲基-5-碘苯合成路线 （共 74 条）
反应条件
methyl pyridin-2-ylmethyl ketone; caesium carbonate; copper(I) bromide in dimethyl sulfoxide T=80°C; 7 h; Inert atmosphere; chemoselective reaction;
参考文献
Zhang, Qi; Wang, Deping; Wang, Xianyang; Ding, Ke
Journal of Organic Chemistry, 2009 , vol. 74, # 18 p. 7187 - 7190
反应条件
caesium carbonate; copper(l) iodide T=110°C; 30 h;
参考文献
Naidu, Ajay B.; Sekar
Tetrahedron Letters, 2008 , vol. 49, # 19 p. 3147 - 3151
反应条件
1: 3,5-dimethylphenyl iodide With indium(III) chloride; chloro-trimethyl-silane; aluminium; lithium chloride in tetrahydrofuran T=25 - 50°C; Inert atmosphere; 2: With zinc diacetate in tetrahydrofuran T=25°C; 0.333333 h; Inert atmosphere; 3: 4-bromo(thiobenzoic) acid S-(4-chlorophenyl) ester With Pd-PEPPSI-IPr in tetrahydrofuran T=25°C; 1 h; Inert atmosphere; chemoselective reaction;
参考文献
Blumke, Tobias; Chen, Yi-Hung; Peng, Zhihua; Knochel, Paul
Nature Chemistry, 2010 , vol. 2, # 4 p. 313 - 318
反应条件
sodium carbonate; 1,2-bis(2'-pyrazineethynyl)benzene palladium dichloride in water; acetonitrile T=70°C; Suzuki coupling; 6 h;
参考文献
Schultheiss, Nate; Barnes, Charles L.; Bosch, Eric
Synthetic Communications, 2004 , vol. 34, # 8 p. 1499 - 1505
反应条件
C34H38Cl2N4Pd; caesium carbonate in 1,4-dioxane T=100°C; Suzuki coupling; 25 h;
参考文献
Morgan, Brad P.; Galdamez, Gabriela A.; Gilliard Jr., Robert J.; Smith, Rhett C.
Dalton Transactions, 2009 , # 11 p. 2020 - 2028
反应条件
copper T=230°C; anschliessende Hydrolyse;
参考文献
Baddar; Gindy
Journal of the Chemical Society, 1948 , p. 1231,1233
反应条件
hydrogen; potassium carbonate in 1,4-dioxane T=120 - 140°C; P=30003 Torr; 20 h; Autoclave;
参考文献
Applied Catalysis A: General, , vol. 469, p. 146 - 152
反应条件
bis-triphenylphosphine-palladium(II) chloride; formic acid; tetra-n-butylammonium tetrafluoroborate in N,N-dimethyl-formamide T=60°C; Carbonylation; P=760 Torr; Electrochemical reaction;
参考文献
Carelli, Italo; Chiarotto, Isabella; Cacchi, Sandro; Pace, Paola; Amatore, Christian; Jutand, Anny; Meyer, Gilbert
European Journal of Organic Chemistry, 1999 , # 6 p. 1471 - 1473
反应条件
copper(I) oxide; ammonium hydroxide in 1-methyl-pyrrolidin-2-one T=80°C; 15 h;
参考文献
Xu, Hanhui; Wolf, Christian
Chemical Communications, 2009 , # 21 p. 3035 - 3037
反应条件
potassium phosphate; copper(l) iodide; (1S,2S)-1,2-diaminocyclohexane in 1,4-dioxane; N-dodecane T=110°C; 24 h;
参考文献
Klapars; Antilla; Huang; Buchwald
Journal of the American Chemical Society, 2001 , vol. 123, # 31 p. 7727 - 7729
