(4R)-4-烯丙基-1-{[(2-甲基-2-丙基)氧基]羰基}-L-脯氨酸合成路线 （共 4 条）
反应条件
1.1: KHMDS; Et3B / tetrahydrofuran; toluene / 0.5 h / -78 °C 1.2: Pd(PPh3)4 / tetrahydrofuran / 1.5 h / -78 - 20 °C 2.1: 63 percent / TFA; H2O / tetrahydrofuran 3.1: LAH / tetrahydrofuran / Heating 4.1: CH2Cl2 / 0 °C 5.1: 88 percent View Scheme
参考文献
Zhang, Rui; Brownewell, Floyd; Madalengoitia, Jose S.
Tetrahedron Letters, 1999 , vol. 40, # 14 p. 2707 - 2710
参考文献
Zhang, Rui; Brownewell, Floyd; Madalengoitia, Jose S.
Tetrahedron Letters, 1999 , vol. 40, # 14 p. 2707 - 2710
反应条件
1: 63 percent / TFA; H2O / tetrahydrofuran 2: LAH / tetrahydrofuran / Heating 3: CH2Cl2 / 0 °C 4: 88 percent View Scheme
参考文献
Zhang, Rui; Brownewell, Floyd; Madalengoitia, Jose S.
Tetrahedron Letters, 1999 , vol. 40, # 14 p. 2707 - 2710
反应条件
1: LAH / tetrahydrofuran / Heating 2: CH2Cl2 / 0 °C 3: 88 percent View Scheme
参考文献
Zhang, Rui; Brownewell, Floyd; Madalengoitia, Jose S.
Tetrahedron Letters, 1999 , vol. 40, # 14 p. 2707 - 2710
