bis(tricyclohexylphosphine)benzylidene ruthenium(IV) dichloride in dichloromethane T=20°C;

1: 54 percent / Grubbs' II Ru catalyst / CH2Cl2 2: 65 percent / PCC / CH2Cl2 View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: 38.4 g / NEt₃ / methanol / 1 h / 60 &deg;C<br />2: 82 percent / DIBAH / CH₂Cl₂ / -80 - -65 &deg;C<br />3: 91 percent / diethyl ether / 4 h / 20 &deg;C<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605283', constants.ctx, '0')">triethylamine</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '110354', constants.ctx, '0')">4-(N,N-dimethlyamino)pyridine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=20&deg;C;&nbsp;3&nbsp;h;&nbsp;<br /> &nbsp;

&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1696894', constants.ctx, '0')">diethyl ether</a> <br />T=20&deg;C;&nbsp;Grignard reaction;&nbsp;4&nbsp;h;&nbsp;<br /> &nbsp;