N-乙氧羰基邻苯二甲酰亚胺合成路线 （共 86 条）
反应条件
triethylamine in N,N-dimethyl-formamide 1. 0-5 deg C, 90 min; 2. room temperature, 4 h;
参考文献
Worster, Paul M.; Leznoff, Clifford C.; McArthur, Colin R.
Journal of Organic Chemistry, 1980 , vol. 45, # 1 p. 174 - 175
反应条件
18-crown-6 ether in toluene T=90°C; 1 h;
参考文献
Soai, Kenso; Ookawa, Atsuhiro; Kato, Kyoko
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 5 p. 1671 - 1672
反应条件
1: 98 percent / TEA / tetrahydrofuran / Heating 2: PCl5 / CH2Cl2 3: aq. NaHCO3 4: 97 percent / H2 / Pd/C / methanol 5: PCl5 / tetrahydrofuran 6: N-ethylmorpholine / tetrahydrofuran View Scheme
参考文献
Chen; Goel; Hyun; Magano; Rubin
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 11 p. 1587 - 1592
反应条件
potassium carbonate in tetrahydrofuran; water T=20°C; 72 h;
参考文献
AC Immune, S.A.
Patent: US2011/280808 A1, 2011 ;
Location in patent: Page/Page column 62 ;
反应条件
0.0833333 h; Heating;
参考文献
Huang, Kenneth He; Ommen, Andy J.; Barta, Thomas E.; Hughes, Philip F.; Veal, James; Ma, Wei; Smith, Emilie D.; Woodward, Angela R.; McCall, W. Stephen
Patent: US2008/269193 A1, 2008 ;
Location in patent: Page/Page column 33 ;
反应条件
potassium carbonate in water T=20°C; 1 h;
参考文献
NOVO NORDISK A/S
Patent: WO2007/115935 A1, 2007 ;
Location in patent: Page/Page column 61 ;
反应条件
sodium carbonate in water 5 h; Ambient temperature;
参考文献
Kolasa, Teodozyj; Miller, Marvin J.
Journal of Organic Chemistry, 1990 , vol. 55, # 14 p. 4246 - 4255
反应条件
1: 225 mg / sodium bicarbonate / H2O / 1 h / Ambient temperature 2: 13 mg / potassium permanganate, sulfuric acid (1 N) / 1 h / Ambient temperature View Scheme
参考文献
Richards, James C.; Spenser, Ian D.
Canadian Journal of Chemistry, 1982 , vol. 60, p. 2810 - 2820
反应条件
sodium carbonate in water T=0 - 20°C; 0.75 h; Inert atmosphere;
参考文献
Organic Process Research and Development, , vol. 9, # 6 p. 853 - 856
反应条件
sodium carbonate in water T=50°C; 1 h;
参考文献
Pinney, Kevin G.; Katzenellenbogen, John A.
Journal of Organic Chemistry, 1991 , vol. 56, # 9 p. 3125 - 3133
